2. 您的位置
3. 首页
4. 会议论文
5. Transgenic zebrafish model of cardiac hypertrophy induced by an AMP-activated protein kinase loss-of

Transgenic zebrafish model of cardiac hypertrophy induced by an AMP-activated protein kinase loss-of

来源 :第11届中国介入心脏病学大会 | 被引量 : 0次 | 上传用户：iezhan

【摘 要】

：

Background We identified a gene (PRKAG2) that encodes the γ-2 regulatory subunit of AMP-activated protein kinase(AMPK) with a novel mutation (Gly100Ser) responsible for PRKAG2 cardiac syndrome (PCS).T

【作 者】

：

ZHANG Bi-li QIN Yong-wen ZHENG Xing ZHAO Xian-xian YE Zhong XU Rong-liang MA Li-ping ZHANG Jian-liang CAO Jiang WU Hong HU Jian-qiang CHEN Shao-ping 

【机 构】

：

Department of Cardiology,Changhai Hospital Second Military Medical University

【出 处】

：

第11届中国介入心脏病学大会

【发表日期】

：

2013年7期

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Background We identified a gene (PRKAG2) that encodes the γ-2 regulatory subunit of AMP-activated protein kinase(AMPK) with a novel mutation (Gly100Ser) responsible for PRKAG2 cardiac syndrome (PCS).The human phenotype consists of ventricular preexcitation, conduction abnormalities, and cardiac hypertrophy.

其他文献

Impact of gender difference on atrial fibrillation risk factors in coal miners

Background Atrial fibrillation (AF) is a serious public health problem resulting in high rates of morbidity and mortality.It had been reported that gender attribute to the increased prevalence of AF,

会议

Treatment of coronary venous dissection in cardiac resynchronization therapy

Background One of the most common complications in the process of implanting left ventricular lead was the coronary venous dissection, whose incidence was about 2 to 4％, being one of the important rea

会议

Role of real-time three-dimensional echocardiography in cardiac resynchronization therapy patients&#

Background This study was to discuss using real-time three-dimensional echocardiography (RT3DE) evaluate left heart function and room wall motion synchronicity in the double ventricular pacing optimiz

会议

Evaluation of pace map for idiopathic right ventricular tachycardia and premature ventricular contra

Background Previous studies have found that the spatial resolution of pace mapping is poor, but can not explain the true mechanism of the defect of pace mapping.In this study, we would observe the map

会议

Impact of the origin of sinoatrial node artery on recurrence after pulmonary vein isolation in aatie

Background Catheter ablation is an effective treatment for patients with paroxysmal atrial fibrillation (AF).Recovered pulmonary vein conduction is a dominant factor in AF recurrence after pulmonary v

会议

Luteolin limits infarct size and improves cardiac function after myocardium ischemia/reperfusion inj

Background The present study was to investigate the effects and mechanism of Luteolin on myocardial infarct size,cardiac function and cardiomyocyte apoptosis in diabetic rats with myocardial ischemia/

会议

Experimental study on effects and mechanisms of aliskiren on ventricular remodeling and heart functi

Background The aim of the study was to investigate the effect and mechanism of aliskiren on ventricular remodeling and heart function in the rats of acute myocardial infarction.Methods The 60 male 8-w

会议

DAA-I inhibits ischemia/reperfusion injury induced apoptosis of cardiac microvascular endothelial ce

Background Acute reperfusion of the jeopardized myocardium results in a cascade of harmful events, referred to as reperfusion injury.Factors contributing to reperfusion injury include cardiomyocytes a

会议

Effects of cardiac contractility modulation applied in different locations of heart on cardiac funct

Background Cardiac contractility modulation (CCM) is a diviced-based therapy which delivery of non-excitatory electrical signals resulting in improved ventricular function.In our study, we stimulate d

会议

Mechanism underlying the inhibitory effect of apelin-13 on glucose deprivation-induced autophagy in

Background Low levels of autophagy plays a protective role in cardiomyoctyes, whereas high levels or chronic autophagy can facilitate cell injury and result in the death of cells that cannot be repair

会议