2. 您的位置
3. 首页
4. 会议论文
5. SPACE EXPERIMENT OF “RAD GENE” IN ISS KIBO: RADIATION EFFECTS IN HUMAN CULTURED CELLS

SPACE EXPERIMENT OF “RAD GENE” IN ISS KIBO: RADIATION EFFECTS IN HUMAN CULTURED CELLS

来源 :第三届亚洲辐射研究大会 | 被引量 : 0次 | 上传用户：alexzc1984

【摘 要】

：

To clarify the biological effects of space environment, especially space radiations, a proposal of "Rad Gene" was performed as the first life science experiment with two human lymphoblastoid cell line

【作 者】

：

Akihisa Takahashi Hiromi Suzuki Katsunori Omori Masaya Seki Toko Hashizume Toru Shimazu Noriaki Ishioka Takeo Ohnishi 

【机 构】

：

Gunma University,Gunma Japan Space Forum,Tokyo;Ka

【出 处】

：

第三届亚洲辐射研究大会

【发表日期】

：

2013年2期

【关键词】

：

Space radiations p53 DNA damage Gene expression Adaptive response 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

To clarify the biological effects of space environment, especially space radiations, a proposal of "Rad Gene" was performed as the first life science experiment with two human lymphoblastoid cell lines bearing wild-type p53 gene (wtp53) and mutated p53 gene (mp53) in an International Space Station (ISS) for 133 days.

其他文献

PULSE RADIOLYSIS STUDIES ON HYDROXYL RADICAL AT EARLY TIME AND IN HIGH TEMPERATURE WATER

Hydroxyl radical (OH) is one of the most important transient species in radical chemistry, radiation chemistry, photochemistry, and many biological processes.

会议

DNA DAMAGE SIGNALING IN RESPONSE TO LOW DOSE RADIATION

The biological effects was assumed to be diverse induced by low dose radiation of 0.5 Gy and lowers.Previously, we have transcriptional profiling of human lyphoblastoid cells after difference γ-rays d

会议

IN VIVO BYSTANDER MECHANISMS IN A MOUSE MODEL BY CHRONIC LOW-DOSE-RATE γ-RAY IRRADIATION

The biological activities of molecules secreted in serum from chronic γ-ray irradiated mice at low or medium-dose-rate (L/MDR) have not been well investigated.

会议

LOW-DOSE AND LOW-DOSE-RATE RADIATION EFFECTS IN EXPERIMENTAL ANIMAL MODEL SYSTEMS

We have been investigated the effect of low-dose-rate radiation (137Cs, 0.7 mGy/h) on DNA repair and other mechanisms in the process of cancer development in AKR/J mice carrying the mouse leukemia vir

会议

TRANSCRIPTION FACTORS POTENTIALLY INVOLVED IN GENE REGULATION AFTER LONG-TERM, LOW DOSE-RATE IRRADIA

Altered gene expression in vivo after low-dose and low-dose-rate irradiation has been observed in a variety of experimental systems.However, few studies actually investigated the underlying mechanisms

会议

low-dose-ratemicroarraygene expressiontranscription factor

FAILED VERIFICATION OF ALZHEIMER'S DISEASE-LIKE ALTERATIONS IN MOUSE BRAIN AFTER EXPOSURE TO LO

Background: A recent study in mice reported early transcriptional response in brain to low-dose X-rays (0.1Gy) suggesting alterations of molecular networks and pathways associated with cognitive funct

会议

Total-Body X-irradiationLow DoseAlzheimer's DiseaseMorris Water Maze Tes

DIINDOLYLMETHANE AS A NOVEL RADIOPROTECTIVE AGENT

3,3-Diindolylmethane (DIM), a small molecule drug-like compound, is a proposed cancer prevention agent that can be safely administered to humans.

会议

DiindolylmethaneRadioprotective agentCancer Treatment

RADIOPROTECTIVE EFFECTS OF A NEW HERBAL COMPOSITION,HEMOHIM, AND ITS APPLICATION

Radiotherapy and chemotherapy have been commonly used for the treatment of cancers,but a variety of side-effects due to the normal tissue damage can be caused.

会议

herbal compositionHemoHIMradioprotectioncisplatinside effect

RADIATION MITIGATORS: AGENTS THAT ARE EFFECTIVE WHEN ADMINISTERED AFTER EXPOSURE

We can classify the compounds that modulate radiation injuries to three categories with respect to the timing of administration: i.e.the compounds for 1) prophylaxis, 2) mitigation, and 3) treatment o

会议

radiation mitigatorvitamin E analogmineral yeast

RADIOPROTECTIVE EFFECTS OF A NOVEL CHIRAL NITROXYL COMPOUND R-1

Objective: Nitroxyl compounds have been reported as potential radioprotection drugs.To develop new radioprotectors, a novel chiral nitroxyl compound R-1 was synthesised.

会议

Nitroxide R-1γ-rayhuman liver cellshuman gastric epithelial cellsradioprotec