Objectives Recently there is accumulating evidence that the wnt/frizzled pathway may play a distinct role in cardiomyocytes apoptosis.We have demonstrated that staurosporine induces cardiomyocytes apo
Objectives To investigate the effects of geminin gene on the proliferation and phenotype of VSMCs in rats by using the siRNA method, and analyse the mechanism of the Geminin gene regulating cells prol
Objectives Ageing increases susceptibility to myocardial ischaemia/reperfusion (I/R) injury.The present study is designed to evaluate the protective effects of ALDH2 activation on I/R tolerance in age
Objectives In vivo, vascular endothelial cells are constantly subjected to and sensitive to fluid shear stress.Shear stress may be the most crucial local factor affecting atherogenesis.Atherosclerotic
Objectives Hyperglycemia during acute myocardial infarction is common and associated with increased mortality.Thioredoxininteracting protein (Txnip) is a modulator of cellular redox stateand contribut
Objectives Primary study have demonstrated that the Angiotensin Ⅱ (Ang Ⅱ) contents and the its receptor density in the kidney of young spontaneously hypertensive rats (SHR) were significantly higher t
Objectives To investigate the effects of Nε-carboxymethyl-Lysine (CML), a key bioactive components of AGEs, on migration from RAW264.7-derived foam cells.Methods The transmembrane migration ability wa
Objectives To explore the mechanism of electrical remodelling and autonomic neural remodelling in acute atrial fibrillation induced by stellate ganglion.
Objectives Increasing evidences shown the important role of bone marrow-derived mesenchymal stem cells (BM-MSCs) in wound healing and vascular remodelling in vivo.However, their mechanism in the devel