pH-induced conformational isomerization of colicin A pore forming domain

来源 :中国化学会生物物理化学专业委员会第四届全国生物物理化学会议 | 被引量 : 0次 | 上传用户:suny112233
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  Colicin A is a bacterial toxin which kills colicin-sensitive bacteria by forming a voltage-gated channel in the cytoplasmic membrane.The pore forming domain of colicin A(ColA-P)is consisting of two hydrophobic helices and eight tightly surrounded amphipathic helices.
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