From Molecular Dynamics to Genomic Biology:Constructing Kinetic Network Models to Elucidate Transcri

来源 :中国化学会生物物理化学专业委员会第四届全国生物物理化学会议 | 被引量 : 0次 | 上传用户：ying8939

【摘要】

：

　　Transcription,the synthesis of RNA from a complementary DNA template,plays a crucial role in cellular regulation,including differentiation,development,and o

【作者】

：

黄旭辉;

【机构】

：

The Hong Kong University of Science and Technology

【出处】

：

中国化学会生物物理化学专业委员会第四届全国生物物理化学会议

【发表日期】

：

2016年期

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　　Transcription,the synthesis of RNA from a complementary DNA template,plays a crucial role in cellular regulation,including differentiation,development,and other fundamental processes.In this talk,I will discuss our results on modeling the RNA polymerase Ⅱ(Pol Ⅱ,a system with～400K atoms)Translocation and other functional conformational changes of this enzyme at sub-millisecond timescales.

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From Molecular Dynamics to Genomic Biology:Constructing Kinetic Network Models to Elucidate Transcri

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