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叶酸是目前临床上应用广泛的维生素 B 族的抗贫血药,叶酸片制剂口服后是否及时显效与溶出度有关,为此,本文对其溶出度的测定方法进行了研究。1、仪器与试药RC—3B 药物溶出仪(天津大学无线电厂),Lambda-6分光光度计(美国 PE 公司),叶酸对照品(卫生部生物制品所),叶酸片(常州制药厂5mg/片),试剂均为分析纯。
Folic acid is currently widely used clinically vitamin B family of anti-anemia drugs, folic acid tablets after oral administration of the timely and effective and dissolution related to this, the dissolution of this paper on the determination of the method were studied. 1, instruments and reagents RC-3B drug dissolution instrument (Tianjin University Radio Factory), Lambda-6 spectrophotometer (the United States PE company), folic acid reference substance (Ministry of Health Institute of Biological Products), folic acid tablets (Changzhou Pharmaceutical Factory 5mg / Tablets), reagents were of analytical grade.