【摘 要】
:
Background There are limited data on dual antiplatelet therapy (DAPT) in blood viscosity.Therefore, we investigated the effect of DAPT on hemarheology in patients with coronary artery disease (CAD) tr
【机 构】
:
Nanjing Medical University,Nanjing First Hospital,Nanjing,China
论文部分内容阅读
Background There are limited data on dual antiplatelet therapy (DAPT) in blood viscosity.Therefore, we investigated the effect of DAPT on hemarheology in patients with coronary artery disease (CAD) treated with drug-eluting stent(DES).Methods From May 2009 to December 2010, 598 consecutive patients with CAD treated by percutaneous coronary intervention (PCI) with DES were prospectively studied.A total of 444 patients included in the analysis from eliminate acute myocardial infarction, acute cerebral infarction, tumor, cor pulmonale, and abnormal hemorrheology, among 214with hemorrheology follow-up.The hemorheology was measured with hemorrheology tester (ZL9000 PLUS), including whole blood viscosity (high era, era, low cut), plasma viscosity, red blood cell deposited, erythrocyte deformation index,red cell aggregation index, and red blood cells electrophoretic time.
其他文献
Background The study was designed to determine that periprocedural intravenous administration of adenosine in acute myocardial infarction patients treated with emergency percutaneous coronary interven
Background As compared with whites, Chinese people more often carry the cytochrome P450 (CYP) 2C19loss-of-function (LOF) allele with the CYP2C193 variant and less carry the cytochrome P450 (CYP) 2C19g
Background Calcium overloading is being thought to be the main reason that leads to cell apoptosis after myocardial treatments.We have paid our efforts in finding the trans-membrane signal mechanisms
Background Increased oxidative stress and vascular inflammation are main mechanisms for no reflow onset after acute ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous c
Background This experimental study was designed to clarify the occurrence of cardiomyocyte apoptosis and its relation with tumor necrosis factor-alpha (TNF-α) expression and cardiac function after cor
Background Multiple evidences indicated that statins exhibit atheroprotective effects greater than those anticipated from LDL-lowering alone.Rosuvastatin has been reported to increase anticoagulants a
Background The failure to deliver a stent across the target lesion during transradial coronary intervention, especially in arteries with calcified tortuous anatomy, is often due to insufficient back-u
Background The Rho/Rho-kinase signaling pathway is known to be involved in the pathogenesis of radial artery spasm.The usefulness of fasudil in combination with conventional vasodilating agents has no
Background Krüppel-like transcription factor 2 (KLF2) has been identified as a key regulator of endothelial antithrombotic function.KLF2 was strongly implicated to be a novel nuclear mediator of stati
Background Myocardial injury occurs frequently in elective percutaneous coronary intervention (PCI) and is associated with subsequent major adverse cardiovascular events (MACE).This study assessed car