目的:观察不同年龄,不同性别大鼠正常及失血性休克后血管反应性和钙敏感性变化。方法:采用失血性休克动物模型,取离体肠系膜上动脉血管环为观察对象,观察4周、7周、10周、14周、18周和半年雌性、雄性大鼠血管反应性和钙敏感性变化,血管反应性和钙敏感性采用离体血管环对梯度浓 Objective: To observe the changes of vascular reactivity and calcium sensitivity in normal and hemorrhagic shock rats of different ages and sexes. Methods: The animal model of hemorrhagic shock was established. The superior mesenteric artery rings were used as the observation objects. The vascular reactivity and calcium sensitivity of the female and male rats at 4 weeks, 7 weeks, 10 weeks, 14 weeks, 18 weeks and 6 months were observed Variations, vasoreactivity and calcium sensitivity were measured using ex vivo vascular rings versus gradient