【摘 要】
：
Subolesin is a well-characterized protective antigen in many ticks,and thus,is potentially useful in the development of a broad-spectrum vaccine or autocidal control strategy using a gene knockdown to
【机 构】
：
Key Laboratory of Animal Parasitology of Ministry of Agriculture,Shanghai Veterinary Research Instit
【出 处】
：
中国畜牧兽医学会兽医寄生虫学分会第十三次学术研讨会
论文部分内容阅读
Subolesin is a well-characterized protective antigen in many ticks,and thus,is potentially useful in the development of a broad-spectrum vaccine or autocidal control strategy using a gene knockdown to control tick infestations.A subolesin homolog was cloned from the Chinese dominant tick Rhipicephalus haemaphysaloides by RACE.Its full length cDNA was 1,386 bp long,containing an ORF of 483 bp with a predicted molecular mass of 18.7 kDa and an isoelectric point of 9.26.The subolesin protein had a typical nuclear localization signal(NLS)signal at its N-terminal region.
其他文献
Toxoplasma gondii can infect all warm-blooded animals including humans.The dense granules proteins play an important role in modifying the environment within the parasitophorous vacuole(PV),associated
Toxoplasma gondii is an obligate intracellular parasite that causes a pathological status known astoxoplasmosis,which has a huge impact on human and animal health.Currently,the main control strategy d
Toxoplasma gondii Glutathione Reductase(TgGR)plays important role during the survival of the parasite.In this investigation,immunological changes and protection efficiency of this protein delivered as
In this study,a DNA vaccine(pTgGST)encoding T.gondii antioxidant glutathione-S-transferase(TgGST)inserted into eukaryotic expression vector pVAX1was constructed and the immune protective efficacy of i
残缘璃眼蜱属于专性外吸血寄生虫,能够传播多种病原体,特别是对环形泰勒虫的传播给畜牧业造成较大的损失。目前蜱的防治越来越多的应用免疫方法,但对残缘璃眼蜱防治的研究较少,同时对媒介蜱传播环形泰勒虫的防控过程研究基本没有；因此,本试验通过对残缘璃眼蜱中肠、唾液腺中的活性分子研究,以期筛选出有效的控蜱及蜱传病候选抗原。本研究以残缘璃眼蜱饥饿成蜱为模板,cys500为引物扩增得到半胱氨酸蛋白酶(Cystei
现已发现苍溪有嗜群血蜱(Haemaphysalis concinna Koch,1844)、长角血蜱(Haemaphysalis longicomis)两种.为了解血蜱在苍溪县的分布、危害、季节活动规律及一些生物学特性.采用宿主体检蜱法、拖旗法、布旗覆盖法采集动物体表和野外环境的蜱,并进行形态鉴定和药物等防制试验.结果显示：1、在2005年,苍溪县发生嗜群血蜱暴发性疫情,流行面达97.4％,动物感
牛瑟氏泰勒虫病是一种广泛分布于世界各地的蜱传性原虫病,感染该病的牛常常会成为病原体的携带者,直接影响牛的健康发育和牛类产品的产量与质量.自然生境中的蜱是牛瑟氏泰勒虫的传播媒介.为了解吉林省东部山区蜱的种类及其携带牛瑟氏泰勒虫的情况,本研究采用布旗法在延吉市、龙井市、珲春市,3个市6个调查位点的自然生境内采集了280只蜱游离蜱类样本的采集并保存70％乙醇中,显微镜下依据经典蜱类形态学种属鉴定蜱的种类
胰岛素受体家族是一类重要的受体酪氨酸激酶(RTKs)。作为起始胰岛素信号传导的第一步，胰岛素(insulin)与胰岛素样生长因子-1(IGF-1)作为配体分别结合至胰岛素受体(IR)与胰岛素样生长因子受体(IGF-1R)的胞外区(ectodomain)并激活细胞膜内酪氨酸激酶活性，在生物体内发挥重要的生理功能。本文概述了胰岛素受体家族(IR和IGF-1R)的结构与功能，并介绍了胰岛素受体家族在寄生
Background: Excretory-secretory products(ESPs)released by helminthes were well-known to regulate the T cell responses such as Th17/Tregs in infected hosts,however their roles in B cells functions rema
为了解我国奶牛的寄生虫情况,收集和整理奶牛的寄生虫相关报告,结果表明我国奶牛的寄生虫有81个虫种,隶属33科48属,其中原虫28种、吸虫26种、绦虫1种、线虫15种、寄生性节肢动物11种.在12个奶牛和5个奶牛养殖小区,采用临床调查、奶牛粪便中寄生虫虫卵或卵囊检测,结果：螨虫病和前后盘吸虫病,各奶牛场和小区均有感染,即比例为100％；片形吸虫病的虫卵阳性场有10个,比例为83.3％,比例范围为4.