【摘 要】
：
The expression level of SLFN11 is causally associated with the activity of DNA-damaging agents in human cancer cells.However, little is known about the mechanism by which this occurs.Here we show that
【机 构】
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Life Sciences Institute and Innovation Center for Cell Signaling Network,Zhejiang University,Hangzho
【出 处】
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The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern
论文部分内容阅读
The expression level of SLFN11 is causally associated with the activity of DNA-damaging agents in human cancer cells.However, little is known about the mechanism by which this occurs.Here we show that SLFN11 interacts directly with RPA1 and is recruited to sites of DNA damage in an RPA1-dependent manner.
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