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The existence of antibiotics and heavy metal co-pollution has become a major environmental issue.In this study,the three three-dimensional biofilm-electrode reactors(3D-BERs)powered by 0.8V voltage were constructed to treat the wastewater containing Zinc(Zn)co-exposure with antibiotics(sulfadiazine(SDZ)and ciprofloxacin(CIP)),antibiotics addition alone or Zn addition alone,respectively.