beta-Adrenoceptors (ARs) in the basolateral nucleus of amygdala (BLA) play an essential role in regulating synaptic plasticity and fear memory.However,little is known about the cellular and subcellular distributions of beta-ARs in this brain structure.Here,we reported that betal-and beta2-ARs are predominantly expressed in neurons but not in astrocytes in the BLA.Interestingly,betal-AR is predominantly distributed in the cell membrane and cytoplasm of neurons,whereas beta2-AR not only in the membrane and cytoplasm but also in the karyon.This differential subcellular distribution of betal-and beta2-ARs may have different functional significance in leaming and memory.