Reduced metabolic activity of gut microbiota by Plateau hypoxia can potentiate the antihypertensive

来源 :2017年第三届岭南国际DMPK论坛 | 被引量 : 0次 | 上传用户:xnlpktg
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
The impact of gut microbiota on the response and metabolism of xenobiotics has been extensively investigated and recognized in recent decades. In particular, gut microbiota have been found to exert various metabolic capabilities which may consequently affect the pharmacodynamics and pharmacokinetics of drugs.
其他文献
Background Cancer has become increasingly prevalent in China over the past few decades.Among symptoms related to the quality of life of cancer patients,pain has commonly been recognized as a most crit
会议
As the most common primary central nervous system tumor,glioma is characterized by high levels of mortality and migration.Unclear boundary with normal brain tissue results in poor treatment.The mammal
Chronic pain is a devastating and distressing experience that can result in mal-adaptive neuroplasticity and negative behavioral consequences,which in turn can result in impaired social function and l
会议
虽1986 年、1996 年世界卫生组织(WHO)发行第一版、第二版癌症治疗,建议类鸦片药物(opioids)按口服、按时,按三阶段方式给予,可解除75 %-85 %癌症疼痛,但剩余15 %-25 %癌症疼痛仍须以fentanyl 贴片、皮下/静脉注射opioids、脊髓注射opioids、神经阻断/神经破坏方式治疗.
会议
Drug transporters are proteins of transmembrane transport in all organs of human. Active transport is its major function.
会议
High mobility group protein 1 and 2 (HMGB1 and HMGB2) are 80% conserved in amino acid sequence.
会议
Hepatocellular Carcinoma (HCC) is the fifth most common cancer and the second most frequent cause of death from cancer worldwide.
会议
Platinum response severely impedes successfully chemotherapy in lung cancer patients.
会议
Drug induced liver injury (DILI), which nowadays is well accepted to include drugs and natural toxins (such as herbal remedies and dietary supplements) induced liver injury, is a severe and potentiall
会议
Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection.
会议