【摘 要】
：
Objective: To investigate the optimal threshold for functional lung (FL) definition of single photon emission computed tomography (SPECT) lung perfusion imaging.Methods: Forty consecutive stage Ⅲ non-
【机 构】
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Department of Radiation Oncology,Shandong Cancer Hospital,Jinan,China
【出 处】
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22nd Asia Pacific Cancer Conference(第22届亚太抗癌大会)
论文部分内容阅读
Objective: To investigate the optimal threshold for functional lung (FL) definition of single photon emission computed tomography (SPECT) lung perfusion imaging.Methods: Forty consecutive stage Ⅲ non-small cell lung cancer(NSCLC) patients obtained SPECT lung perfusion scans and positron emission tomography/computed tomography scans for treatment planning, and the images were co-registered.Total lung and perfusion lung volumes corresponding to 10％ to 60％of the maximum SPECT count were segmented automatically.The SPECT-weighted mean lung dose (SWMDx％) and the percentage of FL volume receiving more than 20 Gy (Fx％V20)of different thresholds were investigated using SPECT-weighted dose-volume histograms.Receiver operator characteristic(ROC) curves were used to identify the SWMD and FV20 of different thresholds in predicting the incidence of radiation pneumonitis (RP).
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