【摘 要】
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Antifungal azoles are widely used for controlling fungal infections.In response azoles stresses, fungi are able to transcriptionally elevate many genes to reduce toxic effects of azoles.However, the r
【机 构】
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State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 10
【出 处】
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中国遗传学会第九次全国会员代表大会暨学术研讨会
论文部分内容阅读
Antifungal azoles are widely used for controlling fungal infections.In response azoles stresses, fungi are able to transcriptionally elevate many genes to reduce toxic effects of azoles.However, the regulatory mechanisms of azole responses in filamentous fungi are poorly understood.In this study, we found that deletion of transcription factor gene CCG-8, which was previously known as a clock-controlled gene, rendered N.crassa hypersensitive to antifungal azoles.
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