2. 您的位置
3. 首页
4. 会议论文
5. Identification of Pathogenic Pathways and Biomarkers for Systemic Lupus Erythematosus Using High-thr

Identification of Pathogenic Pathways and Biomarkers for Systemic Lupus Erythematosus Using High-thr

来源 :2009第四届国际基因组学大会) | 被引量 : 0次 | 上传用户：ksxxccna

【摘 要】

：

Systemic lupus erythematosus (SLE) is a heterogeneous,multisystem autoimmune disease that is associated with organ failure in a significant proportion of patien

【作 者】

：

Quan-Zhen Li 

【机 构】

：

DepartmentofImmunology,GenomicsCoreFacility,UniversityofTexasSouthwesternMedicalCenter,Dallas,Texas7

【出 处】

：

2009第四届国际基因组学大会)

【发表日期】

：

2009年11期

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Systemic lupus erythematosus (SLE) is a heterogeneous,multisystem autoimmune disease that is associated with organ failure in a significant proportion of patients.Genetic predisposition has been proved to be a major component of the disease susceptibility in both human and mouse model.

其他文献

Eat RawFreshIntroducing isotopic Mass-to-charge Ratio and Envelope Fingerprinting (iMEF) and Protein

会议

Genome Instability and DNA Repair Defects in Human Disease

The mammalian DNA-specific exonuclease Trex1 (3repair exonuclease 1,also called DNase Ⅲ) is related to DNA editing enzymes and prevents development of autoimmu

会议

Trex1DNA processingDNA/RNA demethylationFTO

DNA-PKcs is Necessary for Spindle Stability and Mitotic Progression in Response to DNA Damage

When cells are under the stress of genomic DNA damage,a series of cellular responses can be induced,such as apoptosis induction,cell cycle alterations,induced t

会议

The Structure and Function of 9-1-1 Protein Complex

The Rad9-Rad1-Hus1 (9-1-1) complex,evolutionarily conserved from yeast to human,plays crucial roles in DNA repair and cell cycle checkpoint control.The complex

会议

Tolerance of DNA Damage by Translesion DNA Synthesis

Cells that carry unrepaired DNA damage are subject to arrested DNA replication,a lethal event unless the arrest is relieved and normal DNA replication continues

会议

DNA Damage Response Molecule MCPH1 Maintains Mammalian Brain Size by Regulating the Neuroprogenitor

MCPH1/microcephalin is proposed to function in ATM- and ATR-mediated DNA damage response (DDR),and controls cell cycle progression and genomic stability.After i

会议

Dephosphorylation of γ-H2AX by Protein Phosphatases

Reversible protein phosphorylation by kinases and phosphatases is one of the most common mechanisms in controlling most,if not all cellular processes.The phosph

会议

γ-H2AXprotein phosphatasePP4PP6

The Role of DNA Strand Break-sensing Molecule PARP-1 in Neuronal Tumorigenesis

Maintaining genomic integrity through DNA repair is essential to the neuronal function.Cumulative evidence has implied that the central nervous system (CNS) is

会议

Systematic Studies on Plant Small Non-Coding RNAs

Increasing lines of evidence have shown that non-protein coding RNAs,such as microRNAs,siRNAs and antisense RNAs,play important roles in the regulation of plant

会议

From Normal Stem Cells to Cancer Stem Cells—Identifying New Molecular Markers for Cancer Stratificat

Genetic alterations and cytopathological heterogeneity are hallmarks of cancer,in particular glioblastoma multiforme (GBM),contributing to the intractability of

会议