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Objective: Reports investigating the association between genetic polymorphism of glutathione S-transferase T1 (GSTT1) and the risk of rheumatoid arthritis (RA) have revealed conflicting results.To clarify the effect of GSTT1 polymorphism on the risk of developing RA, we carried out a meta-analysis using published data.Methods: Electronic searches were conducted to select studies.Reports were included if they were observational studies investigating the link between GSTT1 genotype and the risk of RA.