Desialylation Induces Apoptosis and Phagocytosis of Platelets in Patients with Prolonged Isolated Th

来源 :中华医学会血液学分会第九次全国造血干细胞移植学术会议 | 被引量 : 0次 | 上传用户:cdtst
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目的 Prolonged isolated thrombocytopenia (PIT) represents a significant complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and is associated with an adverse patient prognosis and higher transplant-related mortality owing to a higher risk of infection events, severe (grades 3 to 4) acute graft-versus-host disease (GVHD) and chronic GVHD.PIT is defined as a peripheral platelet count less than 100× 109/L without sustained anemia or leukopenia for more than 3 months after allo-HSCT (Zhang X, et al.Biol Blood Marrow Transplant, 2011).
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