FMRP regulates NGF-induced axon elongation by targeting axonal Map1b and Calm1 in primary sensory ne

来源 :The 6th FAONS Congress and 11th Biennial Conference of CNS(第 | 被引量 : 0次 | 上传用户：usercmd1

【摘要】

：

Objective Axonal localization of mRNAs and translation are important for axon elongation.Fmr1-encoded protein,FMRP,as a RNA-binding protein(RBP),has been suggested playing a central role in dendritic

【作者】

：

Bin Wang Lin Pan Man-Yi Wei Qiang Wang Nuo-Xin Wang Xing-Yu Jiang Xu Zhang Lan Bao

【机构】

：

State Key Laboratory of Cell Biology,Institute of Biochemistry and Cell Biology,Shanghai Institutes

【出处】

：

The 6th FAONS Congress and 11th Biennial Conference of CNS(第

【发表日期】

：

2015年3期

【关键词】

：

FMRP mRNA local translation axon elongation

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　　Objective Axonal localization of mRNAs and translation are important for axon elongation.Fmr1-encoded protein,FMRP,as a RNA-binding protein(RBP),has been suggested playing a central role in dendritic mRNA targeting,stability and subsequent translation.

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FMRP regulates NGF-induced axon elongation by targeting axonal Map1b and Calm1 in primary sensory ne

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