Organic synthesis and food process frequently produce crude feeds or waste streams containing highly concentrated salt (up to 20%, w/v)[1], which induces many problems in their post-treatment and environment.Nanoffltration (NF) can be a good candidate for desalination of such feeds.However, during NF-desalination process, predictive modeling is difficult due to the effect of salt on retention of organic solutes.Consequently,a better understanding of salt effect on membrane and organic solute is required.