Objective: To investigate the protective effects of Tanshinone ⅡA (Tan ⅡA) on Schwann cells (SCs) mitochondrial apoptosis pathways induced by intermittent high glucose (IHG) and the potential mechanis
目的 优选滋补脾阴方药的水蒸气蒸馏提取工艺。方法 采用单因素考察,以迷迭香酸、异甘草素葡萄糖芹菜苷、丹酚酸B、3,6-二芥子酰基蔗糖、没食子酸、原儿茶醛、甘草苷、远志山酮Ⅲ、3,4,5-三甲氧基肉桂酸、柚皮苷等10种活性成分为考察指标,筛选滋补脾阴方药的水蒸气蒸馏提取工艺。结果 最佳提取工艺为热回流提取1次,2小时,溶剂为90%乙醇。结论 本实验验证了传统复方提取方法的有效性(1次,2小时);而9
目的 建立衰老相关的内质网应激环境的神经干细胞三维培养模型.方法 SD胎鼠脑神经干细胞分离培养;比较不同生物材料作为支架的神经干细胞分化情况.生物材料组包括胞外基质蛋白胶原,胶原+层粘蛋白组,Matrigel,Matrigel+层粘蛋白,Matrigel+层粘蛋白+纳米电纺丝材料nanomatrix.经内质网应激诱导剂衣霉素TM刺激神经干细胞1-3d后,利用免疫荧光法观察神经干细胞marker N
Objective To observe the influence of the compatibility of berberine and evodiamine on liver HMG-CoA reductase (3-hydroxy-3-methyl glutaryl coenzyme A reductase) gene and L-FABP (liver fatty acid bind
Objective Alzheimers disease (AD) is a neurodegenerative diseases, accompanied amyloid plaques and neurofibrillary tangles in hippocampus, cerebral cortex and other areas, which relates to many factor
Objective To investigate effects of Coptis-Evodia herb couple on the expression of HMG-CoA, Liver fatty acid binding protein (L-FABP), lipoproteinlipase(LPL) gene in the liver of hyperlipidemia rats.M
Objective To explore the effect of Tongluo xingnao effervescent tablets on the expression of PGC-1α in multi-infarct dementia rats so that it can supply effective evidences for the clinical experiment
升降散目前已被广泛应用到神经系统疾病的临床治疗中,其清解郁热、调畅气机的功效已得到多位医家的肯定。目前该方主要被应用于头痛、脑血管疾病、睡眠障碍、周围神经病、精神障碍这几大类神经系统疾病,而像癫痫、眩晕、神经系统变性疾病、神经官能症等疾病的临床报道也不少。深入研究该方药理以及更多的临床应用,很可能为神经系统疾病的中医治疗带来新的发现。
Objective(s): To determine the effect of acetylcholine (ACh), pilocarpine, and atropine on pain evoked responses of pain excited neurons (PEN) and pain inhibited neurons (PIN) in hippocampal CA3 regio
目的 观察百会穴针刺加灯盏花穴位注射对卒中后抑郁(PSD)大鼠海马区c-fos蛋白表达的影响.方法 SD雄性大鼠40只,随机分为空白组、PSD模型组、针刺穴注组、氟西汀组;后三组于MCAO术后以CUMS结合孤养法造成PSD模型.针刺穴注组予百会穴针刺加灯盏花注射液穴位注射治疗;氟西汀组予氟西汀水溶液灌胃治疗.四组动物均第56天行无菌断头处死,观察各组大鼠脑组织海马区c-fos蛋白表达.结果 海马区