Phytochemical analysis of the high quality Chinese agarwood Qi-Nan originating from Aquilaria sinensis (Lour.) Glig led to the isolation of a new 2-(2-phenylethyl) chromone derivative, qinanones G (1), and four known 2-(2-phenylethyl)chromones (2-5).Their structures were elucidated by spectroscopic techniques (UV, IR, 1D and 2D NMR) and MS analyses.The NMR data of chromones 1-3 were first reported, and chromones 2 and 3 showed weak inhibitory activity against acetylcholinesterase.