2. 您的位置
3. 首页
4. 会议论文
5. A new change point detection method for identifying DNA copy number variations using NGS read-depth

A new change point detection method for identifying DNA copy number variations using NGS read-depth

来源 :上海交通大学 | 被引量 : 0次 | 上传用户：cppgreate

【摘 要】

：

To study chromosomal aberrations that may lead to cancer formation or genetic diseases,the array-based Comparative Genomic Hybridization(aCGH)technique and the next generation sequencing(NGS)technolog

【作 者】

：

Ayten Yi(g)iter Jie Chen 

【机 构】

：

Department of Statistics,Hacettepe University,Beytepe-Ankara,TURKEY

【出 处】

：

上海交通大学

【发表日期】

：

2016年4期

【关键词】

：

Change point analysis CNV NGS read-depth data Bayesian analysis 

下载到本地 , 更方便阅读

下载此文 赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　To study chromosomal aberrations that may lead to cancer formation or genetic diseases,the array-based Comparative Genomic Hybridization(aCGH)technique and the next generation sequencing(NGS)technology are often used for detecting DNA copy number variations(CNVs).

其他文献

Some Aspects of Multiple Selection Probabilities

In experiments of treatment selections,random samples are drawn from several populations with ordered means.

会议

probability of correct selectionorder statisticsunimodality

Functional Dimension Reduction

To study the relation between a univariate response and multiple functional covariates,we propose a functional single index model that is semiparametric.

会议

Functional Dimension Reduction

Low Rank Graph Regression for Mapping Human Connectome Data

会议

Cross-sectional design with a short-term follow-up for prognostic imaging biomarker

Medical imaging techniques are being rapidly developed and used for diagnosis and prognostic predictions.

会议

case-control studyshort-term follow-upcross-sectional designretrospective stu

Analyzing Heterogeneity in Single Cell RNA-sequencing

会议

Dimension-reduction model-adaptive test for parametric single-index models:A dimension-reduction mod

Local smoothing testing based on multivariate nonparametric regression estimation is one of the main model checking methodologies in the literature.

会议

Dimension reductionparametric single index modelsmodel-adaptionmodel checking

Fisher exact scanning for dependency

We introduce a method—called Fisher exact scanning(FES)—for testing and identifying variable dependency that generalizes Fishers exact test on 2 × 2 tables to larger tables as well as continuous sampl

会议

Big datacontingency tablesmultiple testingmulti-scale modeling

ERRORS IN MULTIPLE TESTING BIG AND SMALL,MORE OR LESS

This presentation highlights some of the errors in multiple testing that have recently come to light.

会议

Multiple testingErrorPermutation testsHazard ratioOdds ratio

Augmented Uniform Designs

Foldover and semifoldover techniques are two important ways to augment the number of runs of a design.

会议

DiscrepancyFoldover designsLower boundsUniform designs

Novel Semiparametric Control Charts for Phase Ⅰ Profile Monitoring via the LM Model Residuals

In typical analyses of data better-modeled by a nonlinear mixed model,an unusual observation(profile),either within a cluster,or an entire cluster itself,can greatly distort parameter estimates and su

会议

Model Robust Profile MonitoringSemiparametricModel Robust RegressionModel Mis