ERp57 modulates mitochondrial calcium uptake through the MCU

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：lwp2007sh

【摘要】

：

【作者】

：

柴真何敬全师维康郭羽

【机构】

：

北京大学生命科学学院生物膜与膜生物工程国家重点实验室,北京 100871

【出处】

：

中国生理学会第24届全国会员代表大会暨生理学学术大会

【发表日期】

：

2014年7期

【关键词】

：

ERp57 MCU Mitochondrial calcium uptake

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　　ERp57 participates in the regulation of calcium homeostasis.Although ERp57 modulates calcium flux across the plasma membrane and the endoplasmic reticulum membrane,its functions on mitochondria are largely unknown.Here,we found that ERp57 can regulate the expression of the mitochondrial calcium uniporter (MCU) and modulate mitochondrial calcium uptake.

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ERp57 modulates mitochondrial calcium uptake through the MCU

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