In 2005, Yue et al.identified four structurally novel lignans Sacidumlignans A-D from Sarcostemma acidum (Roxb.), a plant used in Chinese folk medicine to treat chronic cough and postnatal hypogalactia.[1] Sacidumlignan D shows promising antimicrobial activities against Gram-positive bacteria in vitro.The Ramana and Peng groups have reported the total synthesis of Sacidumlignan D.[2,3] Our synthesis achieved the goal within a promisingly 5 steps and 48％ overall yield from the known diaryl ketone and allylbromide featuring Zn-mediated Barbier Reaction and acid-promoted selective cyclization of diol.