目的:探讨大气细颗粒物(PM2.5)铅成分对SD大鼠血压的影响,并分析其可能机制.方法:将18只雄性SD大鼠(250±50g)随机分为对照组(A组)、硫酸铅组(B组)及卡托普利预处理组(C组),C组染毒前1天100mg/kg卡托普利灌胃,A、B组等剂量生理盐水灌胃,连续3天;根据铅元素在PM2.5的含量,设计硫酸铅染毒剂量84 μ g/kg,B、C组一次性给予硫酸铅气管滴注染毒,A组给予相同剂量生
Objectives Thioredoxin-interacting protein (TXNIP) is a regulator of metabolism and inhibitor of the antioxidant thioredoxins.TXNIP binds thioredxins and is therefore also known as Thioredoxin-binding
Objectives To explore the changes of arotic morphosis expression of microRNA-195 in the aorta of spontaneously hypertensive rats (SHR), and the effect of benazepril on their.Methods 8-week-old male SH
Objectives There are higher prevalence of fatty liver in patients with obstructive sleep apnea syndrome.This study aims to investigate the relationship between nocturnal chronic intermittent hypoxia a
Objectives To investigate the characteristic of blood pressre and its circadian rhythm in chronic kidney disease patients.Methods Clinical data of patients who underwent 24h ambulatory blood pressure
Objectives To investigate the relationship between serum insulin-like growth factor-1 (IGF-1) and brachial-ankle pulse wave velocity (baPWV) in patients with essential hypertension (EH) and the influe
Objectives 1) To investigate the characteristics of blood pressure and its relationship with the incidence of cardiovascular event in patients with essential hypertension (EH) combining coronary heart
Objectives To explore the hypertension history and baseline blood pressure levelson the treatment of atrial fibrillation patients and the impact on one year follow-up cardiovascular outcomes.
Objectives To study the relationship between renal function and left ventricular hypertrophy (LVH) in patients with refractory hypertension (RH), and to investigate the relative risk factors of LVH in
Objectives To investigate the cognitive function status of elderly who were living in nursing houses in northern rural part of China and to explore its related factors.Methods Subjects of study were e