Determination of trace crystal violet by a microdroplet sensor based on surface-enhanced Raman scatt

来源 :第八届全国微全分析系统学术会议、第三届全国微纳尺度生物分离分析学术会议暨第五届国际微化学与微系统学术会议 | 被引量 : 0次 | 上传用户:wangyujing07
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
  Herein we demonstrate a microfluidic platform that integrates a winding microdroplet chip and surface-enhanced Raman scattering (SERS) detection system for trace analysis of crystal violet (CV).Silver colloid was applied to obtain SERS effect.Memory effect can be effectively eliminated in microdroplet system compared to continuous flow microfluidic system.Several parameters,such as flow pattern,droplet size,surfactant effect,detection position etc.were optimized in order to obtain successful droplet and reliable signal.Under the optimal conditions,a good linear correlation in the range of 1.0×10-8 - 8.0×10-7 M with a correlation coefficient (R2) of 0.9967 was obtained.The limit of detection (LOD) of CV in water was estimated to be 3.6 nM.
其他文献
The spread of cancer, either by metastasis to distant organs or local invasion, is the leading cause of most cancer death.For lung cancer diagnosed at an early stage, surgical resection can improve th
会议
The development of embeddable and remotely interrogatable nanomaterials that allow dynamic quantification of intracellular glucose levels can contribute to a better understanding of physiology.We deve
Circulating tumor cells (CTCs) are a kind of tumor cells that can escape from the tumor mass to blood circulation system and further to different tissues of the body at the early stage of malignant pr
Unlike the nanoparticles with surface plasmon resonance,the optical response of polystyrene nanoparticles (PSNPs) is insensitive to the chemical components of the surrounding medium under the waveleng
Hypochlorous acid (HOCl),a key ROS derivative produced by the neutrophil-derived enzyme myeloperoxidase at sites of inflammation,plays a central role in the antimicrobial action,and also implicates in
Phosphorylation is one of the most important post-translation modifications of proteins,it is extensively involved in various physiological processes,including signal conduction,cell cycling and cance
With the development of proteome research,one of the most attractive contemporary endeavors is the pretreatment of peptides/proteins before separation and identification,particularly those with low le
In this paper,we report a simple,low-cost method for rapid,highly reproductive fabrication of paper-based microfluidics by using a commercially available,minitype CO2 laser cutting/engraving machine.T
This study reports the development of a microfluidic beads-based nucleic acid sensor for sensitive detection of circulating tumor cells in the blood using multienzyme-nanoparticle amplification and qu
Microfluidic paper-based analytical devices (μPADs) are emerging as a new technology for point-of-care diagnosis,food analysis and environmental monitoring.In addition to ease of use and dispose,a key