壳聚糖定向修饰多壁碳纳米管微电极阵列

来源 :The 3rd Doctoral Forum of Nanobiology and Medical Science(第三 | 被引量 : 0次 | 上传用户：songlove511

【摘要】

：

【作者】

：

徐辉任王力蒋庭君张松罗津平刘春秀蔡新霞

【机构】

：

中国科学院电子学研究所传感器技术国家重点实验室(北方基地),100190;中国科学院大学,100190

【出处】

：

The 3rd Doctoral Forum of Nanobiology and Medical Science(第三

【发表日期】

：

2014年11期

【关键词】

：

微电极阵列壳聚糖多壁碳纳米管多巴胺 5-羟色胺

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

　　多巴胺(Dopamine,DA)和5-羟色胺(5-Hydroxytryptamine,5-HT)是生物系统中重要的单胺类神经递质.DA广泛分布在脑组织中,用于在哺乳动物中枢神经系统的信息传输,负责大脑的情欲、感觉,传递兴奋信息,也和上瘾有关.DA的缺乏可导致某些神经系统疾病,例如精神分裂症和帕金森氏疾病.5-羟色胺也分布在脑中,参与心血管活动调节、觉醒睡眠周期调节、痛觉调制、精神情感活动和下丘脑垂体的神经内分泌活动的调节.DA和5-HT共存于一个生物系统中,因而同时测定两者是至关重要的.要在活体中准确的测定DA和5-HT是非常困难的,一方面：干扰物质抗坏血酸(AA)具有较高的浓度；另一方面：在裸电极上DA和5-HT的反应电位非常接近,从而获得一个交叠的循环伏安响应,无法判别引起电流响应的神经递质类别.

其他文献

玻璃体切除手术治疗眼后节球内金属异物并发眼内炎的填充物选择

目的：同顾性研究伴玻璃体腔金属异物眼内炎,玻璃体切除手术治疗中玻璃体腔填充物的选择.方法：本研究所选病例是(2008-2013年)我院收治符合本研究排除和纳入标准36人36眼,伴玻璃体腔金属异物眼内炎眼内炎患者.结果：36眼均行玻璃体切除手术, 4眼术中给予BBS填充,4眼中仅有1眼有视网膜点状出血,但无明显视网膜水肿和静脉周围炎.16眼术中给予C3F8填充,其中12眼(75.0％)有锯齿缘离断,

会议

眼内炎球内炎开放性眼外伤眼外伤玻璃体切除手术

Ultra-Small Gold Nanoparticles as Carriers for Nucleus-Based Gene Therapy Due to Size-Dependent Nucl

Nanoscale materials have been catching growing attention in the field of biomedicine.Understanding of the behavior of nanomaterials, especially nanoparticles (NPs) in living system is vitally importan

会议

Ultra-small gold nanoparticlesCancer cell nucleusSize-dependentGene regulatio

Charge Effect on the QDs-peptide Self-assembly Using Fluorescence Coupled Capillary Electrophoresis

We present a molecular characterization of metal-affinity driven self-assembly between CdSe-ZnS quantum dots and a series of hexahistidine peptides appended with different charges.In particular, we ut

会议

Quantum DotsCapillary ElectrophoresisHexahistidine PeptidesCharge Effect

Aligned, modified PHBV/PEO nerve conduits incorporated with laminin promote peripheral nerve regener

Tissue-engineered biomaterial scaffolds for restoring and regenerating damaged peripheral nerve can be designed to mimic complex nerve biological structures, or provide the mechanical support to allow

会议

nerve conduitPHBVlamininsciatic nerve regeneration

A novel electrochemical cytosensor based on Au nanoparticle decorated resin microspheres for sensiti

In this study, for the first time, we report on a facile method for the synthesis and immobilization of AuNPs on m-aminophenol based resin (MAPR) microspheres via a simple reduction route.The AuNPs de

会议

Au nanoparticlem-aminophenolresin microsphereSERSlung cancer cellscytosenso

Studies on the novel photoresponsive hydrogel for 3D cell culture

: As cell culture matrix, animal hydrogel has many drawbacks, such as lots of unknown composition, differences between batches, high cost, etc.The structure of synthetic biomaterial hydrogels is simil

会议

photoresponsivehydrogel3D cell cultureβ-cyclodextrin

Glycyrrhetinic acid-modified liposome with wogonin loaded for hepatic targeting anti-tumor effects

Wogonin (5,7-dihydroxy-8-methoxyflavone, WG, Fig.1) is an attractive candidate for the development of new anti-cancer drugs.WG has been shown to produce anti-cancer effects by increasing cytotoxicity,

会议

WogoninGlycyrrhetinic acidHepatocytesLiposomesAnti-tumor

A novel Gold Nanoflower: preparation, optical properties, biocompatibility and SERS studies

Surface-enhanced Raman (SERS) is currently of study interests due to their unique exact, sensitive, and their stability.Novel Gold nanoparticles structural nanomaterials with different shapes, structu

会议

GoldNanoflowerSERSRaman active probeStabilityBiocompatibility

纳米铂颗粒修饰的植入式脑内葡萄糖微电极阵列

人体的一切生理机能都由大脑支配.大脑内神经活动需要脑中的葡萄糖和氧气提供的能量来维持,因此研究大脑中葡萄糖的代谢对理解脑功能运作的机制有很大的意义.关于脑内葡萄糖的研究有很多,但很多研究采用微量渗析法或金属丝电极.微量渗析法精度高,但成本高,而且也无法高速即时测试.金属丝电极一般是手工制作,无法批量化生产,差异性大.微电子机械系统(MEMS,Micro-Electro-Mechanical Sys

会议

MEMS葡萄糖检测脑内微电极阵列纳米铂颗粒

Galactosylated 3-guanidinopropyl methacrylamide-s-2-hydroxypropyl methacrylamide copolymer as small

Background Gene therapy, especially nucleic acids mediated RNA interference (RNAi), has been use in both basic research and clinical trials.Cationic polymers have often been applied as nucleic acids d

会议

Gene deliverysiRNASurvivinTargeting

壳聚糖定向修饰多壁碳纳米管微电极阵列

与本文相关的学术论文