Relationship between RFC-1 gene polymorphism and methotrexate toxicity in children with acute lympho

来源 :The 35th World Congress of the International Society of Hema | 被引量 : 0次 | 上传用户：chenhaun0702

【摘要】

：

【作者】

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Zaker F Sharafi H Ansari S Farhadi E

【机构】

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Dept of Haematology,School of Allied Medical Science,Iran University of Medical Science

【出处】

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The 35th World Congress of the International Society of Hema

【发表日期】

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2014年5期

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Objective:However methotrexate has a remarkable therapeutic effect in childhood ALL,some patients under treatment of this drug manifest complications in various organs.The aim of this study was to evaluate effect of RFC-I A80G polymorphism on methotrexate toxicity and serum concentration in childhood acute lymphoblastic leukemia.

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Relationship between RFC-1 gene polymorphism and methotrexate toxicity in children with acute lympho

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