【摘 要】
：
Action potentials (APs) are not solely digital form signals because their voltage waveforms are not stereotyped.Here we sought to investigate what determine
【机 构】
：
Institute of Neuroscience,State Key Laboratory of Neuroscience,Shanghai Institutes or Biological Sci
【出 处】
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International Conference for Physiological Sciences 2012(201
论文部分内容阅读
Action potentials (APs) are not solely digital form signals because their voltage waveforms are not stereotyped.Here we sought to investigate what determines the AP waveform and how it is regulated and involved in shaping synaptic transmission.Using dual whole-cell recording from the soma and the axon of neocortical layer V pyramidal cell (PC), we found that somatic depolarization could increase the duration of APs, resulting from inactivation of Kvl channels that selectively distribute at the axon.
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