Identifying Functional Modules for Coronary Artery Disease by a Prior Knowledge-based Approach

来源 :中国卫生统计(生物统计)2014学术年会 | 被引量 : 0次 | 上传用户:seanzhow
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Background: Coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide, is believed to be an inheritable complex disease involving multiple genes and their interactions.Yet until recently, the genetic basis of CAD has been largely unknown, with just a list of genes identified to account for very little of the disease in the population.Hence, to further interpret the underlying molecular mechanisms, systematic dissection of the sophisticated interplays between these individual disease genes and their functional involvements for CAD become essential.
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