In this study, we performed the experiments to explore the beneficial effects of Angelic sinensis polysaccharedes (ASP) on hypoglycemic and hypolipidemic in type 2 diabetic Balb/c mice.
A novel oral mucosal vaccine based on microneedle array has been developd to make a highly safe, stable and potent product with good compliance.Firstly two types of liposomes as a vaccine antigen (Ag)
This work described an eco-friendly approach for the synthesis of sliver nanoparticles (AgNPs) with a water-soluble fraction of polysaccharides (AMWP) extracted from the roots ofAstragalus membranaceu
Aims: The 3243A>G mutation of mtDNA usually is associated with MELAS syndrome.In 3243A>G patients, respiratory chain complex Ⅰ deficiency is most frequently found, and partial decreased amounts of com
Background: Autosomal recessive non-syndromic hearing loss (ARNSHL) is highly heterogeneous, and transmembrane channel-like 1 gene is a disease-causing gene.So far, 35 homozygous mutations in TMC1 wer
先天性唇腭裂(Cleft with or without palate,CL/P)是一种常见的生理缺陷,发病率为1∶500-1∶2500,临床表现为唇裂伴有或者不伴有腭裂.唇腭裂具有高度的遗传异质性,可分为综合征型和非综合征型两种类型.其中非综合征型唇腭裂受基因和环境两种因素共同影响,致病基因及分子病理机制尚不清楚.本研究收集了一个四代遗传的非综合征型唇腭裂家系,该家系共有6位患者,其中有2位表现
肺泡微结石症(pulmonary alveolar microlithiasis,PAM)是一种罕见的肺部疾病,以磷酸钙盐颗粒在肺泡内沉积为特征,有家族遗传倾向,多以常染色体隐性方式遗传.PAM患者早期症状不明显,可在30-40岁之间逐渐出现干咳、呼吸困难、咯血、气胸及肺心病等症状.临床上主要通过X线或胸部CT对PAM进行确诊,患者双肺可见弥漫性砂粒样钙化结节影,且随病情进展钙化灶逐渐增多并出现聚
OBJECTIVE: Sepsis is an inflammatory syndrome caused by infection, and both its incidence and mortality are high.Because interferon-gamma (IFN-γ) plays an important role in inflammation, this work ass
ORMDL sphingolipid biosynthesis regulator 3 (ORMDL3) is a universally confirmed susceptibility gene for asthma and has recently emerged as a crucial modulator in lipid metabolism, inflammation and end
Purpose: Genomic mutations in about 200 genes are associated with hereditary retinal diseases.In this study, we screened for the disease-causing gene mutation in a family with X-linked retinal degener