Radiation shielding structure for C-ADS Inject-Ⅰ was designed and optimized using the FLUKA code.For this equipment was planned to establish in the exsiting tunnel hall and installed in limited space, the beam duct was designed by local shielding structure, the shielding door was made up by combinatorial materials of lead and polyethylene, the cable pipe hole/wave guide hole was shielded through T or U model concrete structure.