论文部分内容阅读
Insights for DNA damage repair: DNA end recognition by the Mre11 nuclease dimer
【机 构】
:
Department of life sciences,Pohang University of Science and Technology,Pohang,South Korea
【出 处】
:
The 16th Ataxia-Telangiectasia Workshop (ATW-2015)6th Intern
【发表日期】
:
2015年期
其他文献
Differential roles of Mre11 nuclease in DNA damage responses in the budding yeast and mammalian cell
Homologous recombination (HR) repairs double-strand breaks (DSBs) generated by radiotherapy and anti-cancer agents such as camptothecin and cisplatin.HR is
会议
Self-assembly of RNF126 into inactive homodimers releases functionally active forms of RNF8 in respo
会议
DNA double-strand break (DSB) is considered most critical lesion among those induced by ionizing radiation (IR).In eukaryotic cells DSB is repaired mainly t
会议
Catalytically inactive Atm abrogates DSB repair more than Atm absence, without causing a marked neur
Cerebellar atrophy is the major, most devastating clinical feature of A-T,characterized by gradual relentless loss of Purkinje and granular neurons.Most ATM
会议
Introduction: Ataxia Telangiectasia (A-T) is a rare genetic disorder with symptoms including ataxia and involuntary movements, telangiectasia, higher risk o
会议
Magnetic Resonance Spectroscopy in the medial parietal grey matter shows no significant difference i
Introduction: Ataxia Telangiectasia (A-T) is a rare genetic disorder with symptoms including ataxia and involuntary movements, higher risk of infections, an
会议
Serum amyloid A protein in patients with ataxia-telangiectasia:biomarker of disease progression? A p
Ataxia-telangiectasia (AT) is an inherited autosomal recessive disorder caused by mutations in the ATM (ataxia-telangiectasia mutated) gene.In spite of prog
会议
Novel compound heterozygous mutations in a child with Ataxia-Telangiectasia showing unrelated cerebe
We report the case of a 6-year-old girl with Ataxia Telangiectasia who developed a left cerebellar astrocytoma and a contralateral cerebellar infarction, th
会议
DNA damage response is required for male fertility.DNA damage repair mediates recombination between homologous chromosomes in meiotic prophase, which is ess
会议
UBE2S, a Novel Substrate of AKT1, Associates with Ku70 and Regulates DNA Repair and Glioblastoma Mul
Glioblastoma multiforme (GBM) is one of the most frequent and lethal cancers.However, the molecular events and their interplay underlying carcinogenesis rem
会议