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  5. Effect of ABCB1 polymorphisms on the adverse clinical events of clopidogrel in Chinese patients with

Effect of ABCB1 polymorphisms on the adverse clinical events of clopidogrel in Chinese patients with

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户：ljj35wmsj
【摘 要】
：
Background The ATP-binding cassette,sub-family B,member 1 (ABCB1) polymorphisms may influence oral bioavailability of clopidogrel and prognosis of patients treated with clopidogrel.The effect of ABCB
【作 者】
：
Zhang Jiahui Yuan Jinqing Meng Xianmin Tang Xiaofang Wang Jing Yao Yi Liu Ruofan Xu Bo Gao Runlin 
【机 构】
：
State Key Laboratory of Cardiovascular Disease,Fuwai Hospital,National Center for Cardiovascular Dis
【出 处】
：
第十二届中国介入心脏病学大会(CIT2014)
【发表日期】
：
2014年3期
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Background The ATP-binding cassette,sub-family B,member 1 (ABCB1) polymorphisms may influence oral bioavailability of clopidogrel and prognosis of patients treated with clopidogrel.The effect of ABCB 1 polymorphisms on the adverse events of clopidogrel treatment have not yet been reported in Chinese patients with ST-elevation myocardial infarction (STEMI).The aim of this study was to investigate the impact of ABCB1 polymorphisms on the risk of ischemic and bleeding events in clopidogrel-treated Chinese patients with STEMI undergoing percutaneous coronary intervention (PCI).
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