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The effects of administration alone or mixed of Angelica keiskei and turmeric extract on blood lipids were evaluated in hypercholesterolemic diet or P-407 induced hyperlipidemic rats.In the study 1,female Sprague-Dawley rats weighing 160-I80g were divided into each groups and fed high cholesterol diets for 8 weeks.Experimental groups were administered with following diets:basal diet (Normal),high cholesterol diets (1% cholesterol).We did the oral administration for evaluation in experimental groups.:C (vehicle),A (angelica extract),T (turmeric extract),AT (angelica extract,turmeric extract / 1∶1 complex).The concentrations of serum total cholesterol,and LDL-cholesterol were decreased by 6.8%,9.8% in A group,by 22.1%,28.8% in C group and by 28.2%,35.6% in AT group,compared to the C group,respectively.