CYP2J2 Attenuates Metabolic Dysfunction in Diabetic Mice by Reducing Hepatic Inflammation via the PP

来源 :2014 International Symposium on Polyunsaturated Fatty Acids | 被引量 : 0次 | 上传用户:hackrx123456789
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  Background and Purpose: Epoxyeicosatrienoic acids (EETs), arachidonic acid-derived cytochrome P450 (CYP) epoxygenase metabolites, have diverse biological effects including anti-inflammatory properties in the vasculature.Increasing evidence suggests that inflammation in type 2 diabetes is a key component in the development of insulin resistance.
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