Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Inhibitor Discovery, Biological Ac

来源 :2015年生物多样性与生态系统国际研讨会 | 被引量 : 0次 | 上传用户：zhouyueying

【摘要】

：

　　Mutations in isocitrate dehydrogenase (IDH),a key enzyme in the tricarboxylic acid cycle,have recently been found in ~75% glioma and ~20% acute myeloid leuk

【作者】

：

Yongcheng Song

【机构】

：

Baylor College of Medicine

【出处】

：

2015年生物多样性与生态系统国际研讨会

【发表日期】

：

2015年期

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　　Mutations in isocitrate dehydrogenase (IDH),a key enzyme in the tricarboxylic acid cycle,have recently been found in ~75% glioma and ~20% acute myeloid leukemia.

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Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases: Inhibitor Discovery, Biological Ac

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