【摘 要】
：
Background: Hco-gal-m and-f were two isoforms of galectin cloned from male and female Haemonchus contortus,respectively,and it was demonstrated that recombinant Hco-gal-m and-f could act as immune sup
【机 构】
：
南京农业大学动物医学院,江苏,南京 210095
【出 处】
：
中国畜牧兽医学会兽医寄生虫学分会第十三次学术研讨会
论文部分内容阅读
Background: Hco-gal-m and-f were two isoforms of galectin cloned from male and female Haemonchus contortus,respectively,and it was demonstrated that recombinant Hco-gal-m and-f could act as immune suppressors.However,little is known about the receptors or binding partners of these galectins in the host.The research of the molecular mechanisms that govern the interactions between these galectins and host molecules will fill a gap in our understanding how parasite galectins interact with host cells.Methods: A yeast two-hybrid system was used to identify the binding partners of Hco-gal-m and-f in this research.The interaction between rHco-gal-m and candidate binding protein was validated by co-immunoprecipitation.
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