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目的探讨影响冷冻胚胎复苏移植妊娠率的因素。方法收集2010年01月到2011年12月份在本中心进行冷冻胚胎解冻移植121个周期的资料,进行回顾性分析。结果 (1)121个周期中有35个周期获临床妊娠,周期临床妊娠率为28.92%;(2)妊娠组与非妊娠组间解冻后胚胎的优质胚胎率有显著性差异(P<0.05);(3)自然周期和激素替代周期间妊娠率无显著性差异(P>0.05),但在激素替代周期中妊娠组与非妊娠组间E2水平有显著性差异(P<0.05);(4)D2及D3冷冻胚胎复苏移植,妊娠率上亦无显著性差异(P>0.05)。结论优质胚胎是冻融胚胎移植周期获得妊娠的关键,在激素替代周期中较高的雌激素水平更有利于胚胎的着床。
Objective To explore the factors affecting the pregnancy rate of frozen embryo resuscitation. Methods A total of 121 cycles of frozen embryo thawing in our center from January 2010 to December 2011 were collected and analyzed retrospectively. Results (1) Clinical pregnancy was achieved in 35 cycles of 121 cycles, with a clinical pregnancy rate of 28.92%. (2) There was a significant difference in the quality of embryos after thawing between pregnant and non-pregnant groups (P <0.05) ; (3) There was no significant difference in the pregnancy rate between the natural cycle and the hormone replacement cycle (P> 0.05), but there was a significant difference in the E2 level between the pregnancy group and the non-pregnancy group in the hormone replacement cycle (P <0.05) There was no significant difference in pregnancy rate between D2 and D3 frozen embryos transplantation (P> 0.05). Conclusion High-quality embryos are the key to obtaining pregnancy during the period of freeze-thaw embryo transfer. Higher estrogen levels in the hormone replacement cycle are more conducive to embryo implantation.