Ascl1 recruits HDAC1 through its N-terminal domain to inhibit mesendoderm formation by VegT in Xenop

来源 :北京细胞生物学会第四次会员代表大会暨2014年年会 | 被引量 : 0次 | 上传用户：borchifish

【摘要】

：

During blastula and gastrula stages ofXenopus embryogenesis,endoderm is specified by the vegetally localized maternal transcription factor VegT,mesoderm is indu

【作者】

：

Gao Li Zhu Xuechen Chen Geng Khand AF Tao Qinghua

【机构】

：

TsinghuaUniversitySchoolofLifeSciences,BeijingChina

【出处】

：

北京细胞生物学会第四次会员代表大会暨2014年年会

【发表日期】

：

2014年11期

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During blastula and gastrula stages ofXenopus embryogenesis,endoderm is specified by the vegetally localized maternal transcription factor VegT,mesoderm is induced to form around the equator mainly by VegT-activated zygotic Nodal signaling,and the animal cells are gradually specified into neural plate in dorsal side and into epidermis in ventral.

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Ascl1 recruits HDAC1 through its N-terminal domain to inhibit mesendoderm formation by VegT in Xenop

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