【摘 要】
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Epithelial-mesenchymal transition (EMT) plays an important role in the pathogenesis of human non-small cell lung cancer (NSCLC).Wnt pathway is identified as a key regulator of normal tissue developmen
【机 构】
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210002 南京军区南京总医院肿瘤内科
【出 处】
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第十六届全国临床肿瘤学大会暨2013年CSCO学术年会
论文部分内容阅读
Epithelial-mesenchymal transition (EMT) plays an important role in the pathogenesis of human non-small cell lung cancer (NSCLC).Wnt pathway is identified as a key regulator of normal tissue development, and its aberrant activation contributes to the process of EMT.Secreted frizzled-related protein 1 (SFRP1), a Wnt signaling antagonist, is frequently downregulated in many tumors including lung cancer.
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