The effects of kolaviron (a methanolic extract of garcinia kola seeds) on hypothalamo-pituitary-gona

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This research work accessed the effects of kolaviron on microantomy of gonad, hypothalamus and anterior pituitary.A total of sixty adult female Wistar rats were used for this experiment.The animals were randomly divided into six groups: A-F.Group A, were control;Group B were given kolaviron (200 mg/kg body weight) once daily;Group C were given kolaviron (100 mg/kg) twice daily;Group D were given clomiphene citrate;Group E were given kolaviron (200 mg/kg) once daily with clomiphene citrate;Group F were given kolaviron (100 mg/kg) with clomiphene citrate.
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