Early,reliable and non-invasive diagnosis of Alzheimer disease(AD)is a great challenge,which makes the prognosis and therapeutic interventions quite difficult.We aimed to investigate the expressions o
Mouse model studies in our laboratory have uncovered mechanisms and treatments for learning and memory disorders,including Neurofibromatosis type I,Tuberous Sclerosis,Noonan Syndrome and DISC1.
Our previous study shows that sodium salicylate(NaSal),a tinnitus inducer,can hyperpolarize the membrane potential of neurons in rat medial geniculate body(MGB),a nucleus in the auditory thalamus(Su e
Patients with damage to the medial temporal lobe show deficits in forming new declarative memories but can still recall older memories,suggesting that the medial temporal lobe is necessary for encodin
Auditory cortical neurons exhibit relatively large variation in their spiking responses to sound stimuli,reflected in the reliability of the response and the precision of the spike timing.
Environmental enrichment,a milieu characterized by increased social interactions,sensory-motor activity,and exploratory behavior,has been demonstrated to enhance structural plasticity in the brain and
Faithful tracking of rapidly successive acoustic signals in the primary auditorycortex (A1) is vital to cortical temporalinformation processing, and is central to the accurateperception of natural sou