论文部分内容阅读
Osteosarcoma is one of the most common types of primary malignant bone tumors in children and adolescents.
Targeted intracellular delivery of shikonin effectively induces osteosarcoma necroptosis with downwa
【摘 要】
：
Osteosarcoma is one of the most common types of primary malignant bone tumors in children and adolescents.
【机 构】
：
Department of Orthopedics,Shanghai First People's Hospital,Shanghai Jiao Tong University,School of
【出 处】
：
Fourth Symposium on Innovative Polymers for Controlled Deliv
【发表日期】
：
2016年11期
其他文献
Multi-functionalized polymeric nanoparticles realized enhanced drug loading efficiency,extended circ
Polymeric nanoparticles (NPs) have been widely studied by numberous groups all over the world,since their great potential to change the landscape of pharmaceutical and biotechnology industries[1].
Multicolor fluorescent carbon nanodots@zeolitic imidazolate framework-8 nanoparticles for simultaneo
Nanoscale building elements are crucial for the design of theranostic platforms that simultaneously detect and treat disease[1].In particular,the major need today is the bifunctional nanoplatforms to
Adhesion of bacteria to surfaces is an essential process in life,and involved in the infection and the organization of biofilms.Thus,bacterial adhesion is relevant in the context of many medical and t
An ideal cancer therapy is to eliminate cancer cells with least damage to normal cells.Monomethyl auristatin E (MMAE),an antimitotic agent inhibiting tubulin polymerization[1],has serve toxicity to tu
Metronidazole (MTZ) is recommended as one of a number of chemotherapy options for the first-line treatment of amoebic colitis.However,it is absorbed rapidly through the upper gastrointestinal tract be
Hyperbranched polysiloxane for highly stretchable and tough hydrogel by one-pot in situ polymerizati
Hydrogel,one of soft materials like elastomers,is consisted of polymer networks and high content of water,and has promising applications in regenerative medicine and biomedical engineering[1].To impro
Efficient therapeutic vaccine needs to strengthen the immune system and eventually eliminate target cells with the help of cytotoxic T lymphocytes (CTLs)[1].In order to achieve such a cellular immunit
An injectable hyaluronic acid/PEG hydrogel produced via copper-free click chemistry for drug deliver
Hyaluronic acid (HA) and polyethylene glycol (PEG) are widely recognized as biocompatible polymers[1],and "Click Chemistry" has the advantage of free of catalyst,no need to heat and can quickly crossl
The emerging treatment of RNA interference (RNAi) has drawn considerable attention from cancer researchers over the past decade because of their distinct ability to silence onco-related genes.However,
Packing nucleic acids inside a single molecule of networked cationic polymer of tunable size,degrada
Although the chemical mechanisms for constructing efficient delivery carriers of nucleic acids are existing in nature as evidenced by the viral ability to deliver genetic materials into host cells of