【摘 要】
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Baekground The Objective of this meta-analysis was to estimate the effect of normal and abnormal ALT on the IFN-alpha based antiviral outcome in na? ve CHC patients.Methods We identified eligible stud
【机 构】
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Peking University Peoples Hospital, Peking University Hepatology Institute
【出 处】
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中华医学会第十六次全国病毒性肝炎及肝病学术会议
论文部分内容阅读
Baekground The Objective of this meta-analysis was to estimate the effect of normal and abnormal ALT on the IFN-alpha based antiviral outcome in na? ve CHC patients.Methods We identified eligible studies by searching the relevant databases, published between January 2000 and May 2010.The selection of eligible papers was carried out using a scoring system based on guidelines and inclusion criteria.Results Seven studies involving a total of 1559 patients were included in our meta-analysis.The Conclusions demonstrated that normal or near-normal baseline ALT levels were associated with a higher rate of SVR in na? ve CHC patients receiving IFN-alpha-based antiviral therapy, (relative risk =1.17, 95％ confidence interval 1.01-1.34, P =0.032).
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