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目的 本研究旨在运用胃癌细胞系及人源化移植瘤(patient-derived xenograft,PDX)模型探讨阿法替尼在胃癌中的抗肿瘤作用和疗效预测标志物,并进一步探索潜在的抗肿瘤机制和获得性耐药机制。
EPHA2抑制剂逆转EPHA2/MAPK信号通路激活介导的阿法替尼对胃癌的获得性耐药
【摘 要】
：
目的 本研究旨在运用胃癌细胞系及人源化移植瘤(patient-derived xenograft,PDX)模型探讨阿法替尼在胃癌中的抗肿瘤作用和疗效预测标志物,并进一步探索潜在的抗肿瘤机制和获得性耐药机制。
【机 构】
：
北京肿瘤医院
【出 处】
：
第十三届全国胃癌学术会议
【发表日期】
：
2018年3期
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