Background: Sui-Zheng-Shi-Liang strategy (regulating prescription dosage with different syndromes) is an important part of syndrome differentiation and treatment in traditional Chinese medicine (TCM).Questionnaires were given to doctors and patients to study the essential factors (indicators and timing) of Sui-Zheng-Shi-Liang strategy in the treatment process of type 2 diabetes (T2DM).Methods: Two questionnaires were designed for diabetes patients and their doctors.