Objective:Renalase is currently the only known amine oxidase in the blood that can metabolize catecholamines and regulate sympathetic activity.High salt intake is associated with high blood pressure (BP), possibly through the modulation of renalase expression and secretion, whereas potassium can reverse the high salt-mediated increase in blood pressure.However, whether potassium could also modulate BP through renalase is unclear.In this study, we aim to investigate how salt intake and potassium supplementation affect the level of renalase in rats.