Mapping Conserved Metazoan Protein Complexes with Biochemical Fractionation and LCMSMS

来源 :第四届中国计算蛋白质组学研讨会 | 被引量 : 0次 | 上传用户：hzn_avr

【摘要】

：

Mechanistic understanding of biology via stable complexes- Proteins mostly work via transient interactions and forming stable machines- Most stable,widespread c

【作者】

：

Cuihong Wan

【机构】

：

Collegeoflifesciences,CentralChinaNormalUniversity

【出处】

：

第四届中国计算蛋白质组学研讨会

【发表日期】

：

2016年8期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

Mechanistic understanding of biology via stable complexes- Proteins mostly work via transient interactions and forming stable machines- Most stable,widespread complexes are unknown Functional characterization of genes- co-memberships predict functions- link genes to phenotypes/diseases,providing hypotheses for therapies

其他文献

从pLink1到pLink2更快、更准的交联肽段鉴定引擎

针对当前鉴定交联肽段存在的问题，通过借助标记技术、可碎裂交联剂、使用高效搜索技术得以解决。实践证实，pLink2速度提升10到20倍，pLink2交联肽段数目提升50％。

会议

蛋白质交联肽段结构鉴定

CHARTING THE CELLULAR INTERACTOME BY PROTEOME-WIDE CROSS-LINKING MASS SPECTROMETRY

Introduction of cross-linking mass spectrometry(XL-MS) XL-MS workflow Maximal distance constraints Introduction of cross-linking mass spectrometry(XL-MS) Proteo

会议

Ultra-deep tyrosine phosphoproteomics enabled by a phosphotyrosine superbinder

Background-Introduction of tyrosine phosphorylation signaling-Enrichment of tyrosine phosphorylation using antibodies Result-Efficient pTyr peptide enrichment b

会议

Genetic dissection of plant architecture and yield-related traits in Brassica napus

　　An optimized plant architecture(PA)is fundamental for high-yield breeding but the genetic control of the important trait is largely unknown in rapeseed.

会议

Comparative transcriptomic analysis uncovers the complex genetic network for resistance to Sclerotin

　　Sclerotinia stem rot caused by Sclerotinia sclerotiorum is one of the most devastating diseases in many important crops including Brassica napus worldwide.

会议

泛素多聚体的四级结构分布及其与靶蛋白相互作用的机制研究

　　蛋白质通过结构的动态变化行使功能。泛素是真核生物中重要的信号蛋白质，它几乎参与所有的生物过程。多个泛素分子可以通过碳端与赖氨酸或者氮端链接形成多聚体，泛素共有八

会议

Dissection of biochemical and genetical bases of rice metabolome using quantitative trait loci analy

　　Plant metabolites are crucial for both plant life and human nutrition.Despite recent advance in metabolomics,natural variation and the underlying genetic co

会议

GAPPa proteogenomic software for genome annotation and global profiling of posttranslational modific

通过建立完整的蛋白质基因组学研究和分析流程,可适用于各种物种；实现了全蛋白质组水平的蛋白质翻译后修饰的系统发现。

会议

蛋白质基因组学学术研究分析流程

Discovery and Characterization of Short-Chain Lysine Acylations with Mass Spectrometry and Quantitat

Lysine - An Abundant and Versatile Amino Acid in Protein Structure and Function Posttranslational Modifications Protein - Protein Interactions Protein Structura

会议

Transcriptome analysis of the compatible and incompatible pollen-stigma interactions in stigma revea

　　Pollen-stigma interactions was the first step of pollination,involves the seeds production in agriculture,evolution and reproductive isolation of species.

会议

self-(in) compatibilitystigmatranscriptomeMS1 geneBrassica napus

Mapping Conserved Metazoan Protein Complexes with Biochemical Fractionation and LCMSMS

与本文相关的学术论文